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别名 | Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol | 储存条件 (自收到货起) |
3年 / -20°C / 粉状 1年 / -80°C / 溶于溶剂 |
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化学式 | C27H44O2 |
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分子量 | 400.64 | CAS号 | 19356-17-3 | |
Solubility (25°C)* | 体外 | DMSO | 80 mg/mL (199.68 mM) | |
Ethanol | 20 mg/mL (49.92 mM) | |||
Water | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
产品描述 | Calcifediol (Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol)是vitamin D3的主要循环代谢产物,是竞争性抑制剂,表观Ki值为3.9 μM,也抑制PTH分泌和mRNA(ED50为2 nM)。 |
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数据来源于[Data independently produced by , , Br J Pharmacol, 2017, 174(16):2636-2651]
Vitamin D supplementation is effective for olanzapine-induced dyslipidemia [ Front Pharmacol, 2023, 14:1135516] | PubMed: 36895943 |
Vitamin D3 suppresses the cholesterol homeostasis pathway in patient-derived glioma cell lines [ FEBS Open Bio, 2023, 13(9):1789-1806] | PubMed: 37489660 |
Vitamin D3 suppresses the cholesterol homeostasis pathway in patient-derived glioma cell lines [ FEBS Open Bio, 2023, 13(9):1789-1806] | PubMed: 37489660 |
FDA-Approved Drug Screening for Compounds That Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish [ Cells, 2021, 10(8)2149] | PubMed: 34440919 |
Vitamin D Regulates MerTK-Dependent Phagocytosis in Human Myeloid Cells [ J Immunol, 2020, ji2000129] | PubMed: 32540991 |
Vitamin D 3 Modulates Yellow Catfish (Pelteobagrus Fulvidraco) Immune Function in Vivo and in Vitro and This Involves the Vitamin D 3/VDR-type I Interferon Axis [ Dev Comp Immunol, 2020, 107:103644] | PubMed: 32061641 |
Roles of Vitamin D and Its Receptor in the Proliferation and Apoptosis of Luteinised Granulosa Cells in the Goat [ Reprod Fertil Dev, 2020, 32(3):335-348] | PubMed: 31708013 |
1,25‑Dihydroxyvitamin D3 enhances the susceptibility of anaplastic thyroid cancer cells to adriamycin‑induced apoptosis by increasing the generation of reactive oxygen species [ Mol Med Rep, 2019, 20(3):2641-2648] | PubMed: 31524258 |
Temperature-dependent vitamin D signaling regulates developmental trajectory associated with diapause in an annual killifish [ Proc Natl Acad Sci U S A, 2018, 115(50):12763-12768] | PubMed: 30446615 |
Potential Use of 1-25-dihydroxyvitamin D in the Diagnosis and Treatment of Papillary Thyroid Cancer [ Med Sci Monit, 2018, 24:1614-1623] | PubMed: 29553126 |
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如果需要长期保存,请于零下二十度低温保存。禁止用于人体及治疗!
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