ACC1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	ACC1 Rabbit Recombinant mAb detects endogenous level of total ACC1.
背景	Acetyl-CoA carboxylase (ACC) is at the junction of lipids synthesis and oxidative metabolic pathways. Acetyl-CoA carboxylases (ACC) are rate-limiting enzymes involved in the de novo synthesis of fatty acids by catalyzing the ATP-dependent carboxylation of acetyl-CoA to generate malonyl-CoA, which is then further converted to long-chain fatty acids by fatty acid synthase (FASN). One of the isofroms of ACC is ACC1, which is located in the cytosol. ACC1 is generally expressed in all tissues, it is expressed more in lipogenic tissues: liver, adipose, and lactating mammary gland. Phosphorylation by AMPK or PKA inhibits the enzymatic activity of ACC.

特异性

ACC1 Rabbit Recombinant mAb detects endogenous level of total ACC1.

背景

Acetyl-CoA carboxylase (ACC) is at the junction of lipids synthesis and oxidative metabolic pathways. Acetyl-CoA carboxylases (ACC) are rate-limiting enzymes involved in the de novo synthesis of fatty acids by catalyzing the ATP-dependent carboxylation of acetyl-CoA to generate malonyl-CoA, which is then further converted to long-chain fatty acids by fatty acid synthase (FASN). One of the isofroms of ACC is ACC1, which is located in the cytosol. ACC1 is generally expressed in all tissues, it is expressed more in lipogenic tissues: liver, adipose, and lactating mammary gland. Phosphorylation by AMPK or PKA inhibits the enzymatic activity of ACC.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

265kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck