Anidulafungin

目录号：S4286 批次号：S428604

化学数据

	别名	LY303366	储存条件 (自收到货起)	3年 -20°C(避光) 粉状
	化学式	C₅₈H₇₃N₇O₁₇
	分子量	1140.24	CAS号	166663-25-8
Solubility (25°C)*	体外	DMSO	100 mg/mL (87.7 mM)
		Ethanol	6 mg/mL (5.26 mM)
		Water	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述

Anidulafungin, 一种echinocandin的衍生物, 抑制glucan synthase的活性, 用作抗真菌药。

靶点

glucan synthase ^[1]

参考文献

[1] Zhanel GG, et al. Antimicrob Agents Chemother, 1997,41(4):863-5.

客户使用selleck产品的实验数据

: 数据来源于[Data independently produced by , , Cell Physiol Biochem, 2016, 38(6):2272-84. ]

Anidulafungin在文献中得到引用

Antiviral Activity of Micafungin and Its Derivatives against SARS-CoV-2 RNA Replication [ Viruses, 2023, 15(2)452]	PubMed: 36851666
Antiviral activity and mechanism of the antifungal drug, anidulafungin, suggesting its potential to promote treatment of viral diseases [ BMC Med, 2022, 20(1):359]	PubMed: 36266654
Synergistic in-vitro antiviral effects of combination treatment using anidulafungin and T-1105 against Zika virus infection [ Antiviral Res, 2021, S0166-3542(21)00178-9]	PubMed: 34648875
Micafungin Inhibits Dengue Virus Infection through the Disruption of Virus Binding, Entry, and Stability [ Pharmaceuticals (Basel), 2021, 14(4)338]	PubMed: 33917182
Hepatic phaeohyphomycosis due to a novel dematiaceous fungus, Pleurostoma hongkongense sp. nov., and importance of antifungal susceptibility testing [ Emerg Microbes Infect, 2020, 1-53]	PubMed: 33337289
Identification of Small-Molecule Inhibitors of Brucella Diaminopimelate Decarboxylase by Using a High-Throughput Screening Assay. [ Front Microbiol, 2020, 10:2936]	PubMed: 32038511
Rare/cryptic Aspergillus species infections and importance of antifungal susceptibility testing [ Mycoses, 2020, 10.1111/myc.13158]	PubMed: 32918365
Inhibiting Fungal Echinocandin Resistance by Small-Molecule Disruption of Geranylgeranyltransferase Type I Activity. [ Antimicrob Agents Chemother, 2020, 64(2)]	PubMed: 31791942
Molecular Identification and Antifungal Susceptibility Profile of Yeast From Vulvovaginal Candidiasis [ BMC Infect Dis, 2020, 19;20(1):287]	PubMed: 32393342
The fungal cell wall as a target for the development of new antifungal therapies. [ Biotechnol Adv, 2019, 37(6):107352]	PubMed: 30797093

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

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