Datasheet

生物描述

特异性	ANP Rabbit Recombinant mAb detects endogenous levels of total ANP.
背景	Atrial natriuretic peptide (ANP) is a small peptide secreted by the heart upon atrial stretch and high systemic blood pressure. The acute effects of this potent, short-lived peptide include increased glomerular filtration and increased renal excretion of sodium and water. These changes may serve to decrease blood volume and subsequently lower blood pressure. In addition to these renal effects, ANP causes both vasodilation, by relaxing vascular smooth muscle, and an acute increase in vascular permeability via receptors on the microvascular endothelium. These mechanisms also decrease blood volume by favoring redistribution of plasma protein and fluid from the vascular space to the interstitial space.

特异性

ANP Rabbit Recombinant mAb detects endogenous levels of total ANP.

背景

Atrial natriuretic peptide (ANP) is a small peptide secreted by the heart upon atrial stretch and high systemic blood pressure. The acute effects of this potent, short-lived peptide include increased glomerular filtration and increased renal excretion of sodium and water. These changes may serve to decrease blood volume and subsequently lower blood pressure. In addition to these renal effects, ANP causes both vasodilation, by relaxing vascular smooth muscle, and an acute increase in vascular permeability via receptors on the microvascular endothelium. These mechanisms also decrease blood volume by favoring redistribution of plasma protein and fluid from the vascular space to the interstitial space.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

15kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Fitz-Roy E. Curry. J Clin Invest. 2005, 115(6): 1458–1461.

Application Data

WB

Validated by Selleck