ASPP2 Rabbit Recombinant mAb

生物描述

特异性

ASPP2 Rabbit Recombinant mAb detects endogenous level of total ASPP2.

背景

ASPP2 is one of three members of the ASPP (apoptosis-stimulating proteins of p53: ankyrin repeats, SH3 domain, and proline-rich region containing protein) family, which specifically stimulates the apoptotic response mediated by the tumor suppressor protein p53. ASPP2 is an interacting partner for a number of proteins, including p53, Bcl-2, RelA p65, Yap, APC-2(APCL), APP-BP1 and protein phosphatase 1 (PP1). All of these proteins, with the exception of APP-BP1, interact with the C-terminal region of ASPP2. In addition, ASPP2 can also regulate autophagy in cancers.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human
MW (kDa)	150kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Virginie Vives, et al. Genes Dev. 2006, 20(10): 1262–1267. [2] Rotem S, et al. J Biol Chem. 2008, 283(27):18990-9. [3] Zhiying Liu, et al. Front Neurosci. 2017, 11: 150.

Application Data

WB

IF