Atg4A Rabbit Recombinant mAb

生物描述

特异性

Atg4A Rabbit Recombinant mAb detects endogenous level of total Atg4A.

背景

Autophagy is an evolutionarily conserved catabolic pathway within all eukaryotic cells that plays a critical housekeeping function to remove senescent or damaged proteins and organelles through lysosome-mediated degradation. Autophagy also plays roles in generating substrates for maintaining cellular energy during times of nutrient insufficiency and hypoxia and in host defenses against intracellular pathogens. Atg4 plays dual roles in the progression of autophagy through the irreversible (proteolytic cleavage) and reversible (lipid deconjugation) modification of Atg8.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse Rat
MW (kDa)	45kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Yang Z, et al. J Biol Chem. 2015, 290(44):26549-61.

Application Data

WB

IHC

IF