Calreticulin Rabbit Recombinant mAb Datasheet

生物描述

特异性	Calreticulin Rabbit Recombinant mAb detects endogenous level of total Calreticulin.
背景	Calreticulin is a highly conserved endoplasmic reticulum chaperone protein which participates in various cellular processes. Calreticulin has been proposed to participate in various physiological and pathological processes in cells. The two major functions of Calreticulin inside the ER are protein chaperoning and regulation of Ca2+ homeostasis. Non-ER Calreticulin regulates important biological functions including cell adhesion, gene expression, and RNA stability. non-ER CRT also plays a crucial role during tumor development. Calreticulin is known as an integrin α-subunit binding protein and it can facilitate β1-integrin activation through influencing integrin glycosylation by FUT1 levels.

特异性

Calreticulin Rabbit Recombinant mAb detects endogenous level of total Calreticulin.

背景

Calreticulin is a highly conserved endoplasmic reticulum chaperone protein which participates in various cellular processes. Calreticulin has been proposed to participate in various physiological and pathological processes in cells. The two major functions of Calreticulin inside the ER are protein chaperoning and regulation of Ca2+ homeostasis. Non-ER Calreticulin regulates important biological functions including cell adhesion, gene expression, and RNA stability. non-ER CRT also plays a crucial role during tumor development. Calreticulin is known as an integrin α-subunit binding protein and it can facilitate β1-integrin activation through influencing integrin glycosylation by FUT1 levels.

使用信息

抗体应用

WB, IHC,ELISA,ELISA

稀释比例

WB	IHC
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

60kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Yi-Chien Lu, et al. BioMed Research International. 2015.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck