CaMKII delta Rabbit Recombinant mAb Datasheet

生物描述

特异性	CaMKII delta Rabbit Recombinant mAb detects endogenous level of CaMKII delta.
背景	Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a multifunctional serine/threonine kinase important for a variety of cellular functions including cell division, differentiation, cardiac contraction, and synaptic plasticity. CaMKII phosphorylation of the AMPA receptor (AMPAR), ryanodine receptor, and several ion channels regulate their conductance properties. Four isoforms have been described (α, β, γ, and δ). CaMKII delta (CaMKIIδ) is the predominant isoform in the heart. It has been found that increases in CaMKIIδ activity causes severe left ventricular dysfunction.

特异性

CaMKII delta Rabbit Recombinant mAb detects endogenous level of CaMKII delta.

背景

Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a multifunctional serine/threonine kinase important for a variety of cellular functions including cell division, differentiation, cardiac contraction, and synaptic plasticity. CaMKII phosphorylation of the AMPA receptor (AMPAR), ryanodine receptor, and several ion channels regulate their conductance properties. Four isoforms have been described (α, β, γ, and δ). CaMKII delta (CaMKIIδ) is the predominant isoform in the heart. It has been found that increases in CaMKIIδ activity causes severe left ventricular dysfunction.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

50kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck