Caspase-14 Rabbit Recombinant mAb

生物描述

特异性

Caspase-14 Rabbit Recombinant mAb detects endogenous level of total Caspase-14.

背景

Caspase-14 is the only member of the caspase family that shows a restricted tissue expression. It is mainly confined to epidermal keratinocytes and in contrast to other caspases, is not activated during apoptosis induced by ultraviolet irradiation or cytotoxic substances. Caspase-14 is responsible for both the correct processing of profilaggrin during cornification and the protection of mice against UVB irradiation. However, caspase-14 is dispensable for keratinocyte apoptosis.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse Rat
MW (kDa)	28kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Rendl M, et al. J Invest Dermatol. 2002, 119(5):1150-5. [2] McIlwain DR, et al. Cold Spring Harb Perspect Biol. 2013, 5(4):a008656.

Application Data

WB

IHC

IF