Cathepsin B Rabbit Recombinant mAb Datasheet

生物描述

特异性	Cathepsin B Rabbit Recombinant mAb detects endogenous level of total Cathepsin B.
背景	Cathepsin B is a cysteine proteinase that primarily functions as an endopeptidase within endolysosomal compartments in normal cells involved in the degradation of cellular proteins in lysosomes. Unlike other cathepsins, cathepsin B functions as an endopeptidase at neutral pH and is also found in extralysosomal sites, including the cytosol, the plasma membrane, and pericellular spaces, where it participates in various cellular processes including cancer metastasis, inflammation, myoblast differentiation, IL-1 production, and cell death.

特异性

Cathepsin B Rabbit Recombinant mAb detects endogenous level of total Cathepsin B.

背景

Cathepsin B is a cysteine proteinase that primarily functions as an endopeptidase within endolysosomal compartments in normal cells involved in the degradation of cellular proteins in lysosomes. Unlike other cathepsins, cathepsin B functions as an endopeptidase at neutral pH and is also found in extralysosomal sites, including the cytosol, the plasma membrane, and pericellular spaces, where it participates in various cellular processes including cancer metastasis, inflammation, myoblast differentiation, IL-1 production, and cell death.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

38kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck