Datasheet

生物描述

特异性	CD32 Rabbit Recombinant mAb detects endogenous levels of total CD32.
背景	The human Fcγ receptors (FcγRI/CD64, FcyγII/CD32, and FcyγIII/CD16) are all members of a family of cell surface molecules that bind the Fc portion of IgG. FcγRI is a high-affinity receptor capable of binding human IgG1, IgG3, and IgG4 in monomeric form. FcγRII and FcγRIII, on the other hand, are low-affinity receptors which bind IgG1 and IgG3 in complexed or aggregated form. Among FcγR, only the FcγRII class is capable of binding human IgG2 efficiently. FcγRII(CD32) is expressed on most myeloid and lymphoid cells, while FCγRIII(CD16) expression is restricted, appearing on NK cells, macrophages, and neutrophils.

特异性

CD32 Rabbit Recombinant mAb detects endogenous levels of total CD32.

背景

The human Fcγ receptors (FcγRI/CD64, FcyγII/CD32, and FcyγIII/CD16) are all members of a family of cell surface molecules that bind the Fc portion of IgG. FcγRI is a high-affinity receptor capable of binding human IgG1, IgG3, and IgG4 in monomeric form. FcγRII and FcγRIII, on the other hand, are low-affinity receptors which bind IgG1 and IgG3 in complexed or aggregated form. Among FcγR, only the FcγRII class is capable of binding human IgG2 efficiently. FcγRII(CD32) is expressed on most myeloid and lymphoid cells, while FCγRIII(CD16) expression is restricted, appearing on NK cells, macrophages, and neutrophils.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

43kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck