CD82 Rabbit Recombinant mAb Datasheet

生物描述

特异性	CD82 Rabbit Recombinant mAb detects endogenous level of total CD82.
背景	The tetraspanin KAI/CD82 is an excellent marker for prospectively isolating stem cells from human fetal and adult skeletal muscle. CD82 physically interacts with alpha7beta1 integrin (α7β1-ITG) and with α-sarcoglycan, a member of the Dystrophin-Associated Glycoprotein Complex (DAPC), both of which have been linked to muscular dystrophies. CD82 has been mostly studied in cancer, as its expression is associated with inhibition of metastasis formation. It also has been reported to maintain the dormancy of hematopoietic stem cells (HSC).

特异性

CD82 Rabbit Recombinant mAb detects endogenous level of total CD82.

背景

The tetraspanin KAI/CD82 is an excellent marker for prospectively isolating stem cells from human fetal and adult skeletal muscle. CD82 physically interacts with alpha7beta1 integrin (α7β1-ITG) and with α-sarcoglycan, a member of the Dystrophin-Associated Glycoprotein Complex (DAPC), both of which have been linked to muscular dystrophies. CD82 has been mostly studied in cancer, as its expression is associated with inhibition of metastasis formation. It also has been reported to maintain the dormancy of hematopoietic stem cells (HSC).

使用信息

抗体应用

WB, IHC,ELISA,ELISA

稀释比例

WB	IHC
1:1000	1:50

反应性

Human Rat

MW (kDa)

30-60kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Alexander MS, et al. Cell Stem Cell. 2016, 19(6):800-807.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck