生物描述

特异性

CDX2 Rabbit Recombinant mAb detects endogenous levels of total CDX2.

背景

CDX2 encodes an intestine-specific transcription factor, normally present throughout embryonic and postnatal life within nuclei of epithelial cells of the intestine from the proximal duodenum to the distal rectum. Using molecular techniques, expression of CDX2 mRNA has been found to be highly restricted to intestinal epithelium. It is crucial for axial patterning of the alimentary tract during embryonic development and is involved in the processes of intestinal cell proliferation, differentiation, adhesion, and apoptosis. CDX2 is considered specific for enterocytes and has been used for the diagnosis of primary and metastatic colorectal adenocarcinoma.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Rabbit
MW (kDa)	40kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Werling RW, et al. Am J Surg Pathol. 2003, 27(3):303-10. [2] Reda S Saad, et al. World J Gastrointest Surg. 2011, 3(11): 159–166.

Application Data

WB

IHC