CXCR7 Rabbit Recombinant mAb Datasheet

生物描述

特异性	CXCR7 Rabbit Recombinant mAb detects endogenous level of total CXCR7.
背景	Chemokine CXCL12 (stromal cell derived factor 1α or SDF-1α) is a key player in angiogenesis and impacts such diverse processes as inflammation, wound healing, embryonic development, and the growth of malignant tumors. CXCL12 promotes tubulogenesis and migration of endothelial cells, including human umbilical endothelial cells (HUVECs) and human microvascular endothelial cells (HMVECs) largely through binding chemokine receptor 4 (CXCR4). CXCR7 is recognized to be a second receptor for CXCL12. CXCR7 is expressed by human endothelial cells, including HUVECs, HMVECs, pulmonary microvascular endothelial cells and endothelial cells within the central nervous system. CXCR7 mediates a broad range of cellular activities, including proliferation, survival, and adhesion by binding with CXCL12.

特异性

CXCR7 Rabbit Recombinant mAb detects endogenous level of total CXCR7.

背景

Chemokine CXCL12 (stromal cell derived factor 1α or SDF-1α) is a key player in angiogenesis and impacts such diverse processes as inflammation, wound healing, embryonic development, and the growth of malignant tumors. CXCL12 promotes tubulogenesis and migration of endothelial cells, including human umbilical endothelial cells (HUVECs) and human microvascular endothelial cells (HMVECs) largely through binding chemokine receptor 4 (CXCR4). CXCR7 is recognized to be a second receptor for CXCL12. CXCR7 is expressed by human endothelial cells, including HUVECs, HMVECs, pulmonary microvascular endothelial cells and endothelial cells within the central nervous system. CXCR7 mediates a broad range of cellular activities, including proliferation, survival, and adhesion by binding with CXCL12.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

41kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck