DDR2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	DDR2 Rabbit Recombinant mAb detects endogenous level of total DDR2.
背景	Discoidin domain receptor 2 (DDR2) is a tyrosine kinase receptor expressed in mesenchymal tissues, the ligand of which is fibrillar collagen. DDR2 is activated upon binding to collagen. It can only be activated by fibrillar collagen, in particular collagens type I, III, and type X. DDR2 can exhibit pro- and anti-proliferative activities in a cell type and context-dependent manner. It can also act as a cell growth inhibitor. DDR2 has been found to promote invasion in prostate, non-small cell lung, breast, and metastatic melanoma.

特异性

DDR2 Rabbit Recombinant mAb detects endogenous level of total DDR2.

背景

Discoidin domain receptor 2 (DDR2) is a tyrosine kinase receptor expressed in mesenchymal tissues, the ligand of which is fibrillar collagen. DDR2 is activated upon binding to collagen. It can only be activated by fibrillar collagen, in particular collagens type I, III, and type X. DDR2 can exhibit pro- and anti-proliferative activities in a cell type and context-dependent manner. It can also act as a cell growth inhibitor. DDR2 has been found to promote invasion in prostate, non-small cell lung, breast, and metastatic melanoma.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

97kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck