Doxycycline

目录号:S5159 批次号:S515902

打印

化学数据

化学结构式 别名 Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum 储存条件
(自收到货起)
3年 / -20°C / 粉状
1年 / -80°C / 溶于溶剂
化学式

C22H24N2O8

分子量 444.43 CAS号 564-25-0
Solubility (25°C)* 体外 DMSO 89 mg/mL (200.25 mM)
Water 45 mg/mL (101.25 mM)
Ethanol Insoluble
体内
(现配现用)
澄清溶液
saline
45.000mg/ml (101.25mM) 以 1 mL 工作液为例,取 45 mg该产品加到1ml生理盐水(0.9% NaCL溶液)中,混合均匀使其澄清,请现配现用!
均匀悬浊液
CMC-NA
≥5mg/ml 以 1 mL 工作液为例,取 5 mg该产品加到 1 ml CMC-NA 溶液中,混合均匀,即可得工作液浓度为 5 mg/ml的均匀悬浊液。
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述 Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum)是一种抗生素,用于治疗由细菌和原生动物引起的多种感染。Doxycycline 也是一种非特异性的 matrix metalloproteinase (MMP) 抑制剂。

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

Doxycycline在文献中得到引用

IGF2BP1 restricts the induction of human primordial germ cell fate in an m6A-dependent manner [ Cell Stem Cell, 2025, S1934-5909(25)00181-X] PubMed: 40436019
RNA-binding proteins DND1 and NANOS3 cooperatively suppress the entry of germ cell lineage [ Nat Commun, 2025, 16(1):4792] PubMed: 40410171
c-JUN: a chromatin repressor that limits mesoderm differentiation in human pluripotent stem cells [ Nucleic Acids Res, 2025, 53(3)gkaf001] PubMed: 39876710
Spatiotemporal dynamics of early oogenesis in pigs [ Genome Biol, 2025, 26(1):2] PubMed: 39748324
EGF-Upregulated lncRNA ESSENCE Promotes Colorectal Cancer Growth through Stabilizing CAD and Ferroptosis Defense [ Research (Wash D C), 2025, 8:0649] PubMed: 40190348
NF-κB-mediated EAAT3 upregulation in antioxidant defense and ferroptosis sensitivity in lung cancer [ Cell Death Dis, 2025, 16(1):124] PubMed: 39987248
Gasdermin D mediates a fast transient release of ATP after NLRP3 inflammasome activation before ninjurin 1-induced lytic cell death [ Cell Rep, 2025, 44(2):115233] PubMed: 40010300
Targeting USP8 causes synthetic lethality through degradation of FGFR2 in ARID1A-deficient ovarian clear cell carcinoma [ NPJ Precis Oncol, 2025, 9(1):69] PubMed: 40074856
Computational prediction and experimental validation identify functionally conserved lncRNAs from zebrafish to human [ Nat Genet, 2024, 56(1):124-135] PubMed: 38195860
Destabilization of fear memory by Rac1-driven engram-microglia communication in hippocampus [ Brain Behav Immun, 2024, 119:621-636] PubMed: 38670239

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品,在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同,大多数建议储存在-20°C,抑制剂属于化学试剂,可在常温下运输储存两周左右。即使如此,我们保证产品的出货量将保持产品质量的条件下,一般都会放入冰袋。望阁下收到产品后,请按照产品数据表建议适当存储。

如果需要长期保存,请于零下二十度低温保存。禁止用于人体及治疗!

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