Fyn Rabbit Recombinant mAb Datasheet

生物描述

特异性	Fyn Rabbit Recombinant mAb detects endogenous level of total Fyn.
背景	Fyn is a protein belonging to the Src family of nonreceptor tyrosine kinases (SFKs), which also includes Src, Yes, Yrk, Blk, Fgr, Hck, Lck, and Lyn. Fyn activity, like that of other Src family kinases, is regulated by intramolecular interactions that depend on equilibrium between tyrosine phosphorylation and dephosphorylation. The biological functions of Fyn are diverse and include processes such as T-cell receptor signaling, cell division and adhesion, platelet function, synaptic function and plasticity, and central nervous system (CNS) myelination. In summary, Fyn regulates key aspects of synaptic physiology. Beyond synaptic function, Fyn has been shown to have a unique role in CNS myelination.

特异性

Fyn Rabbit Recombinant mAb detects endogenous level of total Fyn.

背景

Fyn is a protein belonging to the Src family of nonreceptor tyrosine kinases (SFKs), which also includes Src, Yes, Yrk, Blk, Fgr, Hck, Lck, and Lyn. Fyn activity, like that of other Src family kinases, is regulated by intramolecular interactions that depend on equilibrium between tyrosine phosphorylation and dephosphorylation. The biological functions of Fyn are diverse and include processes such as T-cell receptor signaling, cell division and adhesion, platelet function, synaptic function and plasticity, and central nervous system (CNS) myelination. In summary, Fyn regulates key aspects of synaptic physiology. Beyond synaptic function, Fyn has been shown to have a unique role in CNS myelination.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

60kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Haakon B Nygaard, et al. Alzheimers Res Ther. 2014, 6(1): 8.

Application Data

WB

Validated by Selleck