GABARAP Rabbit Recombinant mAb

生物描述

特异性

GABARAP Rabbit Recombinant mAb detects endogenous level of total GABARAP.

背景

Autophagy is a catabolic process necessary to maintain cellular homeostasis through directing old/damaged organelles (e.g., mitochondria), protein aggregates, and pathogens for lysosomal degradation. In higher eukaryotes, Atg8 has evolved into the LC3/GABARAP protein family, consisting of 7 family proteins [LC3A (2 splice variants), LC3B, LC3C, GABARAP, GABARAPL1, and GABARAPL2]. γ-aminobutyric acid type A (GABAA) receptor-associated protein (GABARAP) is a microtubule-associated protein. GABARAP promotes GABAA receptor clustering. It is a versatile protein with a wide range of interaction partners, which are involved in various aspects of vesicle transport and fusion as well as apoptosis.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	17kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Schaaf MB, et al. FASEB J. 2016, 30(12):3961-3978. [2] Chen L, et al. Proc Natl Acad Sci U S A. 2000, 97(21):11557-62. [3] Ma P, et al. J Biol Chem. 2013, 288(52):37204-15.

Application Data

WB

IHC