Datasheet

生物描述

特异性	GABARAPL2 Rabbit Recombinant mAb detects endogenous level of total GABARAPL2.
背景	GABARAPL2 is a ubiquitin-like protein that is a constituent of the ATG8-conjugation system, one of two evolutionarily conserved phosphatidylethanolamine conjugation systems necessary for the formation of the autophagosome. The human ATG8 system includes seven ubiquitin-like light chain proteins (LCPs) that are homologs of yeast LC3: MAP1LC3A, -B, -C, GABARAP, GABARAPL1, -2, and -3. GABARAPL2 interacts with GABRG2, NSF, GOSR1, beta-tubulin and ULK1. It can be phosphorylated upon DNA damage, probably by ATM or ATR.

特异性

GABARAPL2 Rabbit Recombinant mAb detects endogenous level of total GABARAPL2.

背景

GABARAPL2 is a ubiquitin-like protein that is a constituent of the ATG8-conjugation system, one of two evolutionarily conserved phosphatidylethanolamine conjugation systems necessary for the formation of the autophagosome. The human ATG8 system includes seven ubiquitin-like light chain proteins (LCPs) that are homologs of yeast LC3: MAP1LC3A, -B, -C, GABARAP, GABARAPL1, -2, and -3. GABARAPL2 interacts with GABRG2, NSF, GOSR1, beta-tubulin and ULK1. It can be phosphorylated upon DNA damage, probably by ATM or ATR.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

14kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] UniProt. GABARAPL2.

Application Data

WB

Validated by Selleck