GDNF Rabbit Recombinant mAb

生物描述

特异性

GDNF Rabbit Recombinant mAb detects endogenous level of total GDNF.

背景

Glial cell line-derived neurotrophic factor (GDNF), a member of the TGFβ superfamily that signals via cell-surface tyrosine kinase receptors, is considered an essential neuroprotective ligand for midbrain dopaminergic neurons. GDNF is also shown to have a protective effect against methamphetamine induced dopamine depletion related neurotoxicity. In addition, GDNF has important roles outside the nervous system. It acts as a morphogen in kidney development and regulates the differentiation of spermatogonia.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	24kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Airaksinen MS, et al. Nat Rev Neurosci. 2002, 3(5):383-94.

Application Data

WB

IHC