Islet1 Rabbit Recombinant mAb

生物描述

特异性

JNK2 Rabbit Recombinant mAb detects endogenous level of total JNK2.

背景

JNKs are members of the mitogen-activated protein kinase (MAPK) family, regulating important physiological processes, including neuronal functions, immunological actions, and embryonic development, via their impact on gene expression, cytoskeletal protein dynamics, and cell death/survival pathways. JNK1 and JNK2 are expressed in almost all tissues, but JNK3 expression is largely restricted to the central nervous system. JNK2 is required for phosphorylation of GRASP65-Ser277, and that this phosphorylation is necessary for Golgi fragmentation during the late G2 phase of the cell cycle, and for cell entry into mitosis.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	54kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Zeke A, et al. Microbiol Mol Biol Rev. 2016, 80(3):793-835. [2] Romina Ines Cervigni, et al. J Cell Sci. 2015, 128: 2249-2260.

Application Data

WB

IF