LAMP1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	LAMP1 Rabbit Recombinant mAb detects endogenous level of LAMP1.
背景	The limiting membrane of lysosomes contains a family of highly glycosylated proteins. Lysosome associated membrane protein-1 (LAMP-1) and LAMP-2 are major protein components of the lysosomal membrane. They are type I transmembrane proteins with a large luminal domain, one transmembrane domain and a C-terminal cytoplasmic tail. At steady state, immunoreactive Lamp1 is highly enriched in late endosomes and lysosomes, and so is often used as a marker of these organelles. However, in many cell types Lamp1 immunoreactivity is also present at low levels at the plasma membrane, and can sometimes be detected in early endocytic compartments.

特异性

LAMP1 Rabbit Recombinant mAb detects endogenous level of LAMP1.

背景

The limiting membrane of lysosomes contains a family of highly glycosylated proteins. Lysosome associated membrane protein-1 (LAMP-1) and LAMP-2 are major protein components of the lysosomal membrane. They are type I transmembrane proteins with a large luminal domain, one transmembrane domain and a C-terminal cytoplasmic tail. At steady state, immunoreactive Lamp1 is highly enriched in late endosomes and lysosomes, and so is often used as a marker of these organelles. However, in many cell types Lamp1 immunoreactivity is also present at low levels at the plasma membrane, and can sometimes be detected in early endocytic compartments.

使用信息

抗体应用

WB, IHC,ELISA,ELISA

稀释比例

WB	IHC
1:1000	1:50

反应性

Human

MW (kDa)

120kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck