MALT1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	MALT1 Rabbit Recombinant mAb detects endogenous level of total MALT1.
背景	MALT1 (mucosa-associated lymphoid tissue lymphoma translocation 1), a paracaspase, binds to the adaptor protein Bcl-10, which induces the formation of MALT1 oligomers. MALT1 may be activated through the enforced formation of oligomers. It plays an essential role in the activation of immune cells by specific subtypes of immune receptors, which induce a common signaling pathway leading to the activation of the transcription factor NF-κB. MALT1 is also involved in the activation of non-immune cells, in which an NF-κB response can be induced by specific G protein-coupled receptors (GPCRs) or the epidermal growth factor (EGF) receptor.

特异性

MALT1 Rabbit Recombinant mAb detects endogenous level of total MALT1.

背景

MALT1 (mucosa-associated lymphoid tissue lymphoma translocation 1), a paracaspase, binds to the adaptor protein Bcl-10, which induces the formation of MALT1 oligomers. MALT1 may be activated through the enforced formation of oligomers. It plays an essential role in the activation of immune cells by specific subtypes of immune receptors, which induce a common signaling pathway leading to the activation of the transcription factor NF-κB. MALT1 is also involved in the activation of non-immune cells, in which an NF-κB response can be induced by specific G protein-coupled receptors (GPCRs) or the epidermal growth factor (EGF) receptor.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

92kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck