MIF Rabbit Recombinant mAb Datasheet

生物描述

特异性	MIF Rabbit Recombinant mAb detects endogenous level of total MIF.
背景	Macrophage migration inhibitory factor (MIF) plays a key role in systemic as well as local inflammatory and immune responses. MIF exerts a variety of biologic functions, including macrophage activation, for example, enhancement of adherence, phagocytosis, and tumoricidal activity and induction of nitric oxide (NO) production. MIF is also a unique cytokine, released from monocytes/macrophages in response to glucocorticoids that can counterregulate the immunosuppressive effects of glucocorticoids on the production of other inflammatory cytokines. Thus, MIF functions as a cytokine, an anterior pituitary-derived hormone, and a glucocorticoid-induced immunomodulator. In addition to inflammatory and immunologic functions, MIF is considered to play an essential role in cell proliferation and differentiation and plays an important role throughout developmental processes.

特异性

MIF Rabbit Recombinant mAb detects endogenous level of total MIF.

背景

Macrophage migration inhibitory factor (MIF) plays a key role in systemic as well as local inflammatory and immune responses. MIF exerts a variety of biologic functions, including macrophage activation, for example, enhancement of adherence, phagocytosis, and tumoricidal activity and induction of nitric oxide (NO) production. MIF is also a unique cytokine, released from monocytes/macrophages in response to glucocorticoids that can counterregulate the immunosuppressive effects of glucocorticoids on the production of other inflammatory cytokines. Thus, MIF functions as a cytokine, an anterior pituitary-derived hormone, and a glucocorticoid-induced immunomodulator. In addition to inflammatory and immunologic functions, MIF is considered to play an essential role in cell proliferation and differentiation and plays an important role throughout developmental processes.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

12kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Nishihira J. J Interferon Cytokine Res. 2000, 20(9):751-62.

Application Data

WB

Validated by Selleck