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特异性 | MLKL Rabbit Recombinant mAb detects endogenous level of MLKL. |
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背景 | Mixed lineage kinase domain-like (MLKL) is a substrate for RIPK3 kinase activity and appears to execute the process of necroptosis by targeting the plasma membrane. It is recruited to the necrosome through its interaction with RIP3. RIPK3 can phosphorylate several residues in the activation loop of MLKL, including Ser345, Ser347 and Thr349. |
抗体应用 | WB,ELISA,ELISA | ||
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稀释比例 |
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反应性 | Human | ||
MW (kDa) | 54kDa | ||
抗体类型 | Rabbit | ||
储存液配方 | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. | ||
储存条件 (自收到货起) |
Store at –20°C. |
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WB
Validated by Selleck