MSI2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	MSI2 Rabbit Recombinant mAb detects endogenous level of total MSI2.
背景	Musashi (MSI) are neural RNA-binding proteins. Musashi (MSI) family proteins control cell proliferation and differentiation in many biological systems. They are over-expressed in tumors of several origins, and their expression level correlates with poor prognosis. MSI proteins control gene expression by binding RNA and regulating its translation. They contain two RNA recognition motif (RRM) domains, which recognize a defined sequence element. There are two mammalian MSI family members: MSI1 and MSI2. MSI1 is expressed in neural and glial progenitor cell as well as in progenitors of several epithelial tissues. MSI2 is 69% identical to MSI1 and is expressed in a partially overlapping set of tissues.

特异性

MSI2 Rabbit Recombinant mAb detects endogenous level of total MSI2.

背景

Musashi (MSI) are neural RNA-binding proteins. Musashi (MSI) family proteins control cell proliferation and differentiation in many biological systems. They are over-expressed in tumors of several origins, and their expression level correlates with poor prognosis. MSI proteins control gene expression by binding RNA and regulating its translation. They contain two RNA recognition motif (RRM) domains, which recognize a defined sequence element. There are two mammalian MSI family members: MSI1 and MSI2. MSI1 is expressed in neural and glial progenitor cell as well as in progenitors of several epithelial tissues. MSI2 is 69% identical to MSI1 and is expressed in a partially overlapping set of tissues.

使用信息

抗体应用

WB, IHC,ELISA,ELISA

稀释比例

WB	IHC
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

35kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Zearfoss NR, et al. J Biol Chem. 2014, 289(51):35530-41.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck