MYBBP1A Rabbit Recombinant mAb detects endogenous levels of total MYBBP1A

MYBBP1A was originally identified as a protein interacting with the leucine zipper of c-Myb. This protein has been reported to bind to several transcription factors, including the aromatic hydrocarbon receptor, PGC-1α, NF-κB, and Prep1, and to regulate their activity. MYBBP1A is ubiquitously expressed and is a nuclear protein mainly localized to the nucleolus. It shares some homology with a yeast protein called POL5, reported to be an essential DNA polymerase in Saccharomyces cerevisiae. MYBBP1A also plays an essential role in the normal progression of mitosis.