NUR77 Rabbit Recombinant mAb Datasheet

生物描述

特异性	NUR77 Rabbit Recombinant mAb detects endogenous level of total NUR77.
背景	Orphan nuclear receptor Nur77 (also known as TR3) belongs to the subfamily 4, group A (NR4A) of nuclear receptors and has important roles in metabolism and energy balance in a context-dependent manner. Nur77 has multiple effects on glucose metabolism. It was reported to stimulate gluconeogenesis in liver as a transcriptional modulator, promote glucose utilization through the upregulation of gene expression and enhance insulin sensitivity in skeletal muscle.

特异性

NUR77 Rabbit Recombinant mAb detects endogenous level of total NUR77.

背景

Orphan nuclear receptor Nur77 (also known as TR3) belongs to the subfamily 4, group A (NR4A) of nuclear receptors and has important roles in metabolism and energy balance in a context-dependent manner. Nur77 has multiple effects on glucose metabolism. It was reported to stimulate gluconeogenesis in liver as a transcriptional modulator, promote glucose utilization through the upregulation of gene expression and enhance insulin sensitivity in skeletal muscle.

使用信息

抗体应用

WB, IHC,ELISA,ELISA

稀释比例

WB	IHC
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

64kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Zhan YY, et al. Nat Chem Biol. 2012, 8(11):897-904.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck