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特异性 | PABPN1 Rabbit Recombinant mAb detects endogenous level of total PABPN1. |
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背景 | The polyadenosine RNA binding protein, polyadenylate-binding nuclear protein 1 (PABPN1), plays key roles in post-transcriptional processing of RNA. PABPN1 is ubiquitously expressed and presumably contributes to control of gene expression in all tissues. In addition to ensuring proper polyadenylation, PABPN1 also excutes additional cellular activities. PABPN1 shuttles between the nucleus and the cytoplasm, it can modulate post-transcriptional regulation of messenger RNAs and the processing of long non-coding RNAs (lncRNAs). PABPN1 has been implicated in the cellular processes that could be altered in Oculopharyngeal Muscular Dystrophy. |
抗体应用 | WB, IHC, IF,ELISA,ELISA | ||||||
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稀释比例 |
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反应性 | Human Mouse | ||||||
MW (kDa) | 49kDa | ||||||
抗体类型 | Rabbit | ||||||
储存液配方 | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. | ||||||
储存条件 (自收到货起) |
Store at –20°C. |
WB
Validated by Selleck
IHC
Validated by Selleck
IF
Validated by Selleck