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目录号:A2008 批次号: A200801
Pertuzumab (anti-HER2)是一种人源单价克隆抗体,抑制HER2二聚化、破坏HER2与其他HER家族成员结合的能力。MW: 148 KD。
CAS号 | 380610-27-5 |
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配制 | PBS buffer, pH 7.2 |
推荐同型对照 | Human IgG1 |
来源 | CHO cells |
储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
纯度 | 99.10% |
蛋白浓度 | 5.0 mg/ml |
内毒素 | ≤1 EU/mg |
Multi-Targeting Anticancer Activity of a New 4-Thiazolidinone Derivative with Anti-HER2 Antibodies in Human AGS Gastric Cancer Cells [ Int J Mol Sci, 2023, 24(7)6791] | PubMed: 37047765 |
The effect of the alpha-specific PI3K inhibitor alpelisib combined with anti-HER2 therapy in HER2+/PIK3CA mutant breast cancer [ Front Oncol, 2023, 13:1108242] | PubMed: 37469415 |
Establishment and large-scale validation of a three-dimensional tumor model on an array chip for anticancer drug evaluation [ Front Pharmacol, 2022, 13:1032975] | PubMed: 36313330 |
Optical biosensor based on weak value amplification for the high sensitivity detection of Pertuzumab in combination with Trastuzumab binding to the extracellular domain of HER2 [ Opt Express, 2022, 30(20):36839-36848] | PubMed: 36258605 |
Anti-HER2 monoclonal antibodies intensify the susceptibility of human gastric cancer cells to etoposide by promoting apoptosis, but not autophagy [ PLoS One, 2021, 16(8):e0255585] | PubMed: 34437575 |
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma [ Nat Commun, 2020, 11(1):1556] | PubMed: 32214092 |
WEE1 inhibitor, AZD1775, overcomes trastuzumab resistance by targeting cancer stem-like properties in HER2-positive breast cancer. [ Cancer Lett, 2020, 472:119-131] | PubMed: 31866466 |
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