PGC1 beta Rabbit Recombinant mAb Datasheet

生物描述

特异性	PGC1 Rabbit Recombinant mAb detects endogenous level of total PGC1.
背景	PGC1β is a transcriptional coactivator that potently stimulates mitochondrial biogenesis and respiration of cells. PGC1β has a wide tissue distribution, but it is most highly expressed in tissues of high oxidative metabolism such as brown adipose tissue (BAT), heart and skeletal muscle. It coactivates a broad range of nuclear receptors/transcriptional factors. In addition, PGC1β strongly promotes mitochondrial proliferation and cell respiration in muscle cells. PGC1β is a major regulator of mitochondrial metabolism.

特异性

PGC1 Rabbit Recombinant mAb detects endogenous level of total PGC1.

背景

PGC1β is a transcriptional coactivator that potently stimulates mitochondrial biogenesis and respiration of cells. PGC1β has a wide tissue distribution, but it is most highly expressed in tissues of high oxidative metabolism such as brown adipose tissue (BAT), heart and skeletal muscle. It coactivates a broad range of nuclear receptors/transcriptional factors. In addition, PGC1β strongly promotes mitochondrial proliferation and cell respiration in muscle cells. PGC1β is a major regulator of mitochondrial metabolism.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

113kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Claudia R. Vianna, et al. Cell Metab. 2006, 4(6): 453–464.

Application Data

WB

Validated by Selleck