生物描述

特异性

Placental alkaline phosphatase (PLAP) Rabbit Recombinant mAb detects endogenous levels of total placental alkaline phosphatase.

背景

Placental alkaline phosphatase (PLAP) is a cellsurface-associated sialoglycoprotein enzyme normally present at high concentrations on the syncitiotrophoblast plasma membrane. Ectopic expression of PLAP is associated with cancer of ovary, testis, lung, and colorectal tract. It is usually used as a tumor marker, especially in seminoma and ovarian cancer. However, PLAP is reliable only in non-smokers, as smoking interferes with measurement of PLAP.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human
MW (kDa)	70kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Hamilton-Dutoit SJ, et al. APMIS. 1990, 98(9):797-811. [2] Sérvio T. Stinghen, et al. J Biomed Biotechnol. 2006, 2006: 56087.

Application Data

WB

IHC