PMS2 Rabbit Recombinant mAb

生物描述

特异性

PMS2 Rabbit Recombinant mAb detects endogenous level of total PMS2.

背景

PMS2 is an essential component of DNA mismatch repair (MMR) complexes, which play an important role in maintaining genetic stability. MMR functions primarily in the detection and repair of mismatched bases that result from erroneous replication, and also plays important roles in DNA damage response, genetic recombination, control of meiotic progression, and generation of antibody diversity. PMS2 is a latent endonuclease that introduces additional nicks into the discontinuous DNA strand of nicked heteroduplex substrates.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human
MW (kDa)	110kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Hidewaki Nakagawa, et al. Molecular Biology, Pathobiology, and Genetics. 2004, 64(14):4721-4727. [2] van Oers JM, et al. Proc Natl Acad Sci U S A. 2010, 107(30):13384-9.

Application Data

WB

IHC

IF