Prion Protein Rabbit Recombinant mAb

生物描述

特异性

Prion Protein Rabbit Recombinant mAb detects endogenous level of total Prion Protein.

背景

The prion protein (PrP) is an N-glycosylated protein attached to the outer leaflet of eukaryotic cell membranes via a glycosylphosphatidylinositol (GPI) anchor. Posttranslational modifications (PTMs) of PrP influence conversion of cellular prion protein (PrPC) into PrPSc. The cellular prion protein (PrPC) is a cell surface protein expressed in a variety of different organs and tissues with high expression levels in the central and peripheral nervous systems. The misfolding of the cellular prion protein (PrPC) causes fatal neurodegenerative diseases.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	28kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Laura Westergard, et al. Biochim Biophys Acta. 2007, 1772(6): 629-644. [2] Wulf MA, et al. BMC Biol. 2017, 15(1):34.

Application Data

WB

IHC