RAB7 Rabbit Recombinant mAb Datasheet

生物描述

特异性	RAB7 Rabbit Recombinant mAb detects endogenous level of total RAB7.
背景	Rab7 is a late endosome-/lysosome-associated small GTPase and plays critical roles in the endocytic processes. Through interaction with its partners (including upstream regulators and downstream effectors), Rab7 participates in multiple regulation mechanisms in endosomal sorting, biogenesis of lysosome and phagocytosis. These processes are closely related to substrates degradation, antigen presentation, cell signalling, cell survival and microbial pathogen infection. Rab7 also plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Trafficking disorders, resulting from mutation or dysfunction of Rab7, can cause human diseases, and the Rab7-mediated membrane traffic process is linked to pathogen infection and survival.

特异性

RAB7 Rabbit Recombinant mAb detects endogenous level of total RAB7.

背景

Rab7 is a late endosome-/lysosome-associated small GTPase and plays critical roles in the endocytic processes. Through interaction with its partners (including upstream regulators and downstream effectors), Rab7 participates in multiple regulation mechanisms in endosomal sorting, biogenesis of lysosome and phagocytosis. These processes are closely related to substrates degradation, antigen presentation, cell signalling, cell survival and microbial pathogen infection. Rab7 also plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Trafficking disorders, resulting from mutation or dysfunction of Rab7, can cause human diseases, and the Rab7-mediated membrane traffic process is linked to pathogen infection and survival.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

23kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck