SATB1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	SATB1 Rabbit Recombinant mAb detects endogenous level of total SATB1.
背景	Special AT-rich binding protein 1 (SATB1) is a nuclear matrix attachment region (MAR) DNA-binding protein which acts as a genome organizer and gene regulator through modulating the spatial conformation of chromatin. It also participates in a variety of biologically important processes such as proliferation, differentiation, apoptosis and the reprogramming of expression profiles. The upregulation of SATB1 has been found to be correlated with invasion and metastasis of many types of malignances, including gastric cancer, breast cancer, rectal cancer, liver cancer, and prostate cancer.

特异性

SATB1 Rabbit Recombinant mAb detects endogenous level of total SATB1.

背景

Special AT-rich binding protein 1 (SATB1) is a nuclear matrix attachment region (MAR) DNA-binding protein which acts as a genome organizer and gene regulator through modulating the spatial conformation of chromatin. It also participates in a variety of biologically important processes such as proliferation, differentiation, apoptosis and the reprogramming of expression profiles. The upregulation of SATB1 has been found to be correlated with invasion and metastasis of many types of malignances, including gastric cancer, breast cancer, rectal cancer, liver cancer, and prostate cancer.

使用信息

抗体应用

WB, IHC,ELISA,ELISA

稀释比例

WB	IHC
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

100kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Feng Wan, et al. PLoS One. 2015, 10(2): e0117518.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck