SMC1 Rabbit Recombinant mAb

生物描述

特异性

SMC1 Rabbit Recombinant mAb detects endogenous level of total SMC1.

背景

Structural maintenance of chromosome protein 1 (SMC1) is well known for its roles in sister chromatid cohesion and DNA repair. It is a rod-shaped molecule with an ABC-like ATPase at one end and dimerization domain at the other connected by long coiled-coil regions. SMC1 localized to centrosomes throughout the cell cycle in a microtubule-independent manner. In addition to the nuclear location, SMC1 was also reported present in cytoplasm. SMC1 may play important roles in nucleation or anchoring of microtubules at interphase of the cell cycle and abscission at the final stage of cytokinesis.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse Rat
MW (kDa)	143kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Guan J, et al. Biochem Biophys Res Commun. 2008, 372(4):761-4.

Application Data

WB

IHC

IF