SOD2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	SOD2 Rabbit Recombinant mAb detects endogenous level of total SOD2.
背景	The Superoxide dismutases (SODs) are a family of enzymes that very efficiently catalyze the dismutation of the superoxide radical anion. SODs have been implicated in many disease states including inflammatory diseases, diseases of ischemia and reperfusion, neurodegenerative diseases, and cancer, as well as more subtle roles in cell signaling and perhaps in immune function. SOD1 is located in the cytosol of eukaryotic cells. SOD2 is localized in the matrix of mitochondria, which convert O2⋅– to H2O2, which is further metabolized to H2O by glutathione peroxidase. SOD2 plays an important role in protection against cellular damage by ionizing radiation.

特异性

SOD2 Rabbit Recombinant mAb detects endogenous level of total SOD2.

背景

The Superoxide dismutases (SODs) are a family of enzymes that very efficiently catalyze the dismutation of the superoxide radical anion. SODs have been implicated in many disease states including inflammatory diseases, diseases of ischemia and reperfusion, neurodegenerative diseases, and cancer, as well as more subtle roles in cell signaling and perhaps in immune function. SOD1 is located in the cytosol of eukaryotic cells. SOD2 is localized in the matrix of mitochondria, which convert O2⋅– to H2O2, which is further metabolized to H2O by glutathione peroxidase. SOD2 plays an important role in protection against cellular damage by ionizing radiation.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

25kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck