UBE2I Rabbit Recombinant mAb

生物描述

特异性

UBE2I Rabbit Recombinant mAb detects endogenous level of total UBE2I.

背景

UBE2I is a SUMO-conjugating enzyme, also known as UBC9. It is a sole E2 enzyme and involved in the pathway protein sumoylation, which is part of protein modification. It is reported that UBE2I is required for reprogramming as its suppression dramatically inhibits iPS cell induction. It plays a critical role in reprogramming fibroblasts to iPS cells and maintaining ESC pluripotency. UBE2I (Ubc9) is a pivotal regulator of the subcellular targeting and turnover of GLUT4 in adipocytes. It regulates the insulin responsiveness of glucose transport mainly through modulation of the amount and subcellular targeting of GLUT4.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	18kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Tahmasebi S, et al. Stem Cells. 2014, 32(4):1012-20. [2] Liu LB, et al. Diabetes. 2007, 56(8):1977-85.

Application Data

WB

IF