ULK3 Rabbit Recombinant mAb Datasheet

生物描述

特异性	ULK3 Rabbit Recombinant mAb detects endogenous level of total ULK3.
背景	ULK3 belongs to unc-51-like family of serine/threonine kinases and shares similarity with STK36 and dFu proteins. It is an autophosphorylated kinase and phosphorylates GLI proteins in vitro. ULK3 is involved in Shh pathway as a positive regulator of Gli proteins. ULK3 is widely expressed. Its expression is higher in a number of tissues where Shh signaling is known to be active, such as fetal and postnatal brain and liver. Within the adult brain, higher expression of ULK3 is found in hippocampus, olfactory bulb, cerebellum and optic nerve.

特异性

ULK3 Rabbit Recombinant mAb detects endogenous level of total ULK3.

背景

ULK3 belongs to unc-51-like family of serine/threonine kinases and shares similarity with STK36 and dFu proteins. It is an autophosphorylated kinase and phosphorylates GLI proteins in vitro. ULK3 is involved in Shh pathway as a positive regulator of Gli proteins. ULK3 is widely expressed. Its expression is higher in a number of tissues where Shh signaling is known to be active, such as fetal and postnatal brain and liver. Within the adult brain, higher expression of ULK3 is found in hippocampus, olfactory bulb, cerebellum and optic nerve.

使用信息

抗体应用

WB, IF,ELISA,ELISA

稀释比例

WB	IF
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

53kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Maloverjan A, et al. Exp Cell Res. 2010, 316(4):627-37.

Application Data

WB

Validated by Selleck

IF

Validated by Selleck