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别名 | N/A | 储存条件 (自收到货起) |
3年 -20°C 粉状 | |
化学式 | C14H21N3O |
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分子量 | 247.34 | CAS号 | 146986-50-7 | |
Solubility (25°C)* | 体外 | DMSO | 49 mg/mL (198.1 mM) | |
Ethanol | 49 mg/mL (198.1 mM) | |||
Water | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
产品描述 | Y-27632是一种选择性ROCK1和ROCK2抑制剂,无细胞试验中Ki分别为140 nM和300nM,比对其他激酶包括PKC,cAMP依赖性蛋白激酶,MLCK和PAK的作用强200多倍。 | ||||
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Ancestral allele of DNA polymerase gamma modifies antiviral tolerance [ Nature, 2024, 10.1038/s41586-024-07260-z] | PubMed: 38570685 |
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons [ Cell Stem Cell, 2024, S1934-5909(24)00094-8] | PubMed: 38626772 |
Bioelectric stimulation controls tissue shape and size [ Nat Commun, 2024, 15(1):2938] | PubMed: 38580690 |
Nongenetic Optical Modulation of Pluripotent Stem Cells Derived Cardiomyocytes Function in the Red Spectral Range [ Adv Sci (Weinh), 2024, 11(3):e2304303] | PubMed: 37948328 |
An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders [ Mol Neurodegener, 2024, 19(1):31] | PubMed: 38576039 |
Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer [ Cell Rep Med, 2024, 5(2):101396] | PubMed: 38290515 |
Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition [ J Exp Clin Cancer Res, 2024, 43(1):88] | PubMed: 38515178 |
Biosafe cerium oxide nanozymes protect human pluripotent stem cells and cardiomyocytes from oxidative stress [ J Nanobiotechnology, 2024, 22(1):132] | PubMed: 38532378 |
Genetic and functional correction of argininosuccinate lyase deficiency using CRISPR adenine base editors [ Am J Hum Genet, 2024, 111(4):714-728] | PubMed: 38579669 |
Cell mechanics regulate the migration and invasion of hepatocellular carcinoma cells via JNK signaling [ Acta Biomater, 2024, S1742-7061(24)00036-9] | PubMed: 38272199 |
特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品,在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同,大多数建议储存在-20°C,抑制剂属于化学试剂,可在常温下运输储存两周左右。即使如此,我们保证产品的出货量将保持产品质量的条件下,一般都会放入冰袋。望阁下收到产品后,请按照产品数据表建议适当存储。
如果需要长期保存,请于零下二十度低温保存。禁止用于人体及治疗!
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