• PDE1
  • PDE2
  • PDE3
  • PDE4
  • PDE5
  • PDE6
  • PDE10A
  • PDE9
  • PDE4B

PDE2 抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S6433 Udenafil Udenafil is a potent antagonist of human PDE5 with an IC50 of 8.25 nM and a comparable selectivity profile as sildenafil for the other PDEs. Pan PDE2, IC50: 101 nM
S4837 Ibudilast Ibudilast (KC-404, AV411, MN166) is a relatively non-selective phosphodiesterase inhibitor with anti-inflammatory and neuroprotective activities. Pan PDE2, IC50: 0.11 μM
S2484 Milrinone Milrinone (Win 47203,Primacor) is a phosphodiesterase 3 (PDE3) inhibitor, used to increase the heart's contractility. Pan PDE2, IC50: 5.2 μM
S2320 Luteolin Luteolin (Luteoline, Luteolol, Digitoflavone) is a flavonoid found in Terminalia chebula, which is a non-selective phisphodiesterase PDE inhibitor for PDE1-5 with Ki of 15.0 μM, 6.4 μM, 13.9 μM, 11.1 μM and 9.5 μM, respectively. Pan PDE2, Ki: 6.4 μM
S5539 Olprinone Olprinone is a phosphodiesterase III (PDE3) inhibitor with IC50 values of 0.35 mM, 150 mM and 100 mM for human cardiac PDE III, PDE I and PDE II, respectively. Pan PDE2, IC50: 100 mM
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