所有产品
| 目录号 | 产品名 | 产品描述 |
|---|---|---|
| S7311 | Q-VD-Oph | Q-VD-Oph (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a potent pan-caspase inhibitor with IC50 ranged from 25 to 400 nM for caspases 1,3,8, and 9. Q-VD-OPh can inhibits HIV infection. |
| E3549 | Qamgur Extract | Qamgur Extract is extracted from Brassica rapa, which can prevent sleep-deprivation induced cognitive deficits via the inhibition of neuroinflammation and mitochondrial depolarization. |
| S0163 | Qstatin | QStatin is a potent and selective inhibitor of SmcR (V. harveyi LuxR homologue) with an EC50 of 208.9 nM, binding tightly to SmcR and changes the flexibility of the protein, thereby altering its transcription regulatory activity, which can be a sustainable antivibriosis agent useful in aquacultures. |
| E3394 | Quassia Extract | Quassia Extract is extracted from Quassia, which can be used in the treatment of diabetes and associated dyslipidemia. |
| E0675 | Quercetagetin | Quercetagetin (6-Hydroxyquercetin), a flavonoid, is a moderately potent and selective, cell-permeable Pim-1 kinase inhibitor with IC50 of 0.34 μM. |
| S2391 | Quercetin | Quercetin, a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. Quercetin induces mitophagy, apoptosis and protective autophagy. Phase 4. |
| S3281 | Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside | Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside (Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobiosiden, Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside) is an active constituent of Descurainiae Semen. |
| E0210 | Quercetin 3-O-β-D-glucuronide | Quercetin 3-O-β-D-glucuronide (Miquelianin, Q3GA) is one of the quercetin metabolites with antioxidant activity. |
| S2347 | Quercetin Dihydrate | Quercetin (Sophoretin), a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. Quercetin (dihydrate), a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively. |
| S3824 | Quercitrin | Quercitrin (3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities. |
| S5741 | Quetiapine | Quetiapine(ICI204636) is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.Quetiapine is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine have moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.23, 5.74, 7.54, 5.55. |
| S1763 | Quetiapine (ICI-204636) fumarate | Quetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors. |
| E3858 | Quillaia Extract | Quillaia Extract is extracted from Quillaja, which may be used as a foaming agent in soft drinks. |
| S9019 | Quillaic acid | Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and shows strong anti-inflammatory activity. |
| S4255 | Quinacrine 2HCl | Quinacrine 2HCl(Quinacrine dihydrochloride) is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. Quinacrine is an effective phospholipase A2 inhibitor. |
| S5435 | Quinacrine Dihydrochloride Dihydrate | Quinacrine (Mepacrine) is a dye of the acridine family that has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug. |
| S6366 | Quinaldic acid | Quinaldic acid is a product of l-tryptophan catabolism, via kynurenic acid, found in human urine. |
| S2581 | Quinapril HCl | Quinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM. |
| S3671 | Quinestrol | Quinestrol (Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566) is a synthetic, steroidal estrogen which is used in hormone replacement therapy and occasionally to treat breast cancer and prostate cancer. |
| S3886 | Quinic acid | Quinic acid (Chinic acid, Kinic acid) is a crystalline acid obtained from cinchona bark, coffee beans, and other plant products and made synthetically by hydrolysis of chlorogenic acid. |
| S3751 | Quinidine hemisulfate hydrate | Quinidine hemisulfate hydrate(Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial. |
| S4681 | Quinidine hydrochloride monohydrate | Quinidine hydrochloride monohydrate is an anti-arrythmic agent and a potent potassium channel inhibitor with IC50 of 19.9 μM. |
| S4495 | Quinine | Quinine, an alkaloid derived from the bark of the cinchona tree, is an anti-malaria agent and a potassium channel inhibitor that inhibits mSlo3 (KCa 5.1) channel currents evoked by voltage pulses to +100 mV with IC50 of 169 μM. |
| S2502 | Quinine HCl Dihydrate | Quinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria. |
| E4105 | Quinizarin | Quinizarin (1,4-Dihydroxyanthraquinone) is a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode. It is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth. |
| E3412 | Quinoa Extract | Quinoa Extract is extracted from Chenopodium quinoa Willd., which is used for the prevention and treatment of obesity and obesity-associated disorders. |
| S5202 | Quinocetone | Quinocetone is a novel veterinary chemicals that is also bacteriocide and potential anti-tumor agent. |
| S6095 | Quinoline-4-carboxylic acid | Quinoline-4-carboxylic acid (4-Carboxyquinoline) is a very important structure in a synthetic medicinal chemistry. |
| S3624 | Quinolinic acid | Quinolinic Acid (pyridine-2,3-dicarboxylic acid, QUIN), a neuroactive metabolite of the kynurenine pathway, is an agonist of N-methyl-D-aspartate (NMDA) receptor. |
| E0818 | Quinupristin | Quinupristin, a streptogramin antibiotic, blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits. |
| S1096 | Quisinostat (JNJ-26481585) 2HCl | Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2. |
| S1526 | Quizartinib (AC220) | Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3. |
| S7848 | QX-314 chloride | QX-314 chloride directly activates and permeates the human isoforms of TRPV1 and TRPA1 to induce inhibition of sodium channels. |
| S6797 | QX77 | QX77 is a novel activator of chaperone-mediated autophagy (CMA). QX77 induces the up-regulation of Rab11 expression and up-regulates LAMP2A expression. |
