Spartalizumab (anti-PD-1)

目录号:A2017 别名: PDR001 中文名称:斯巴达珠单抗

For research use only.
Not for use in humans.

Spartalizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合。PDR001可与PD-1以高亲和力结合,抑制其生物活性;MW: 145.8 KD。

规格 价格 库存 购买数量  
RMB 1957.78 现货
RMB 5790.61 现货
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客户使用Selleck该产品发表文献1篇:

质量管理及产品安全说明书

PD-1/PD-L1抑制剂选择性比较

生物活性

产品描述 Spartalizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合。PDR001可与PD-1以高亲和力结合,抑制其生物活性;MW: 145.8 KD。
靶点
PD-1 [1]
()
体内研究 In phase 1/2 studies, PDR001 has a manageable safety profile and preliminary antitumor activity in advanced solid tumors[1].

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

抗体信息

CAS No. 1935694-88-4
配制 PBS buffer, pH 7.2
同型 Human IgG4
来源 CHO cells
储存条件 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles

技术支持

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常见问题及建议解决方法

  • 问题1:

    How to store the antibody?

  • 回答:

    Store the undiluted solution at 4 °C in the dark. Freezing antibodies can result in a loss of activity caused by the freezing/thawing process. Diluting antibodies to working concentrations and storing at 4°C for more than a day should be avoided. Additionally, make sure to keep the antibody sterile. Under these storage conditions, your antibodies should remain active for up to one year and oftentimes longer.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID