Prostaglandin E2 (PGE2)

目录号：S3003 批次号：S300303

化学数据

	别名	Dinoprostone	储存条件 (自收到货起)	3年 / -20°C / 粉状 1年 / -80°C / 溶于溶剂
	化学式	C₂₀H₃₂O₅
	分子量	352.47	CAS号	363-24-6
Solubility (25°C)*	体外	DMSO	70 mg/mL (198.59 mM)
		Ethanol	70 mg/mL (198.59 mM)
		Water	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述	Prostaglandin E2 (PGE2, Dinoprostone) 在分娩中发挥重要作用（可软化宫颈，引起子宫收缩），也刺激成骨细胞释放能刺激破骨细胞吸收的因子。

参考文献

[1] Fernandez-Repollet E, et al. J Histochem Cytochem. 1982 May;30(5):466-70.

Prostaglandin E2 (PGE2)在文献中得到引用

Anti-angiogenic therapy using the multi-tyrosine kinase inhibitor Regorafenib enhances tumor progression in a transgenic mouse model of ß-cell carcinogenesis [ Br J Cancer, 2023, 10.1038/s41416-023-02389-6]	PubMed: 37620408
Anti-angiogenic therapy using the multi-tyrosine kinase inhibitor Regorafenib enhances tumor progression in a transgenic mouse model of ß-cell carcinogenesis [ Br J Cancer, 2023, 129(8):1225-1237]	PubMed: 37620408
Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer [ JCI Insight, 2023, 8(6)e156057]	PubMed: 36757813
The cyclooxygenase-expressing mesenchyme resists intestinal epithelial injury by paracrine signaling [ Cell Regen, 2023, 12(1):30]	PubMed: 37574502
The cyclooxygenase-expressing mesenchyme resists intestinal epithelial injury by paracrine signaling [ Cell Regen, 2023, 12(1):30]	PubMed: 37574502
PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis [ Bone Res, 2022, 10(1):27]	PubMed: 35260562
Macrophages evoke autophagy of hepatic stellate cells to promote liver fibrosis in NAFLD mice via the PGE2/EP4 pathway [ Cell Mol Life Sci, 2022, 79(6):303]	PubMed: 35588334
CD96 Downregulation Promotes the Immune Response of CD4 T Cells and Associates with Ankylosing Spondylitis [ Biomed Res Int, 2022, 2022:3946754]	PubMed: 35769669
Cross-species single-cell transcriptomic analysis reveals divergence of cell composition and functions in mammalian ileum epithelium [ Cell Regen, 2022, 11(1):19]	PubMed: 35511361
Inhibition of cyclooxygenase-2 enhanced intestinal epithelial homeostasis via suppressing β-catenin signalling pathway in experimental liver fibrosis [ J Cell Mol Med, 2021, 10.1111/jcmm.16730]	PubMed: 34145945

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