14-3-3 Rabbit Recombinant mAb Datasheet

生物描述

特异性	14-3-3 Rabbit Recombinant mAb detects endogenous level of total 14-3-3.
背景	The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. More than 50 signaling proteins have been reported as 14-3-3 ligands. This broad range of partners suggests for 14-3-3 a role as a general biochemical regulator, reminiscent of the well-defined regulatory protein calmodulin. Through interaction with its effector proteins, 14-3-3 participates in the regulation of diverse biological processes, including neuronal development, cell growth control, and viral and bacterial pathogenesis. Within a eukaryotic cell, 14-3-3 is largely found in the cytoplasmic compartment. However, 14-3-3 proteins can also be detected at the plasma membrane and in intracellular organelles such as the nucleus and the Golgi apparatus

特异性

14-3-3 Rabbit Recombinant mAb detects endogenous level of total 14-3-3.

背景

The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. More than 50 signaling proteins have been reported as 14-3-3 ligands. This broad range of partners suggests for 14-3-3 a role as a general biochemical regulator, reminiscent of the well-defined regulatory protein calmodulin. Through interaction with its effector proteins, 14-3-3 participates in the regulation of diverse biological processes, including neuronal development, cell growth control, and viral and bacterial pathogenesis. Within a eukaryotic cell, 14-3-3 is largely found in the cytoplasmic compartment. However, 14-3-3 proteins can also be detected at the plasma membrane and in intracellular organelles such as the nucleus and the Golgi apparatus

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

28kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Fu H, et al. Annu Rev Pharmacol Toxicol. 2000, 40:617-47.

Application Data

WB

Validated by Selleck