Acyclovir (Aciclovir)

目录号：S1807 批次号：S180704

化学数据

	别名	Acycloguanosine, ACV, NSC 645011,BW 248U	储存条件 (自收到货起)	3年 / -20°C / 粉状 1年 / -80°C / 溶于溶剂
	化学式	C₈H₁₁N₅O₃
	分子量	225.2	CAS号	59277-89-3
Solubility (25°C)*	体外	DMSO	45 mg/mL (199.82 mM)
		Water	Insoluble
		Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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生物活性

产品描述

Acyclovir (Aciclovir)是一种合成的核苷类似物，有效作用于疱疹病毒。Acyclovir 可在Jurkat白血病细胞中诱导细胞周期紊乱和凋亡。

靶点

HSV ^[1]

参考文献

客户使用selleck产品的实验数据

: 数据来源于[Data independently produced by , , Oncol Rep, 2017, 37(4):2109-2120]

Acyclovir (Aciclovir)在文献中得到引用

Topical phenylbutyrate antagonizes NF-κB signaling and resolves corneal inflammation [ iScience, 2022, 25(12):105682]	PubMed: 36536680
Prevention of Herpesviridae Infections by Cationic PEGylated Carbosilane Dendrimers [ Pharmaceutics, 2022, 14(3)536]	PubMed: 35335912
Safety, efficacy and delivery of multiple nucleoside analogs via drug encapsulated carbon (DECON) based sustained drug release platform [ Eur J Pharm Biopharm, 2022, S0939-6411(22)00047-9]	PubMed: 35314347
Harringtonine Inhibits Herpes Simplex Virus Type 1 Infection by Reducing Herpes Virus Entry Mediator Expression [ Front Microbiol, 2021, 12:722748]	PubMed: 34531841
6-Thioguanine Inhibits Herpes Simplex Virus 1 Infection of Eyes [ Microbiol Spectr, 2021, 9(3):e0064621]	PubMed: 34730435
A natural product, (S)-10-Hydroxycamptothecin inhibits pseudorabies virus proliferation through DNA damage dependent antiviral innate immunity [ Vet Microbiol, 2021, 265:109313]	PubMed: 34968801
Pharmaceutically Acceptable Carboxylic Acid-Terminated Polymers Show Activity and Selectivity against HSV-1 and HSV-2 and Synergy with Antiviral Drugs [ ACS Infect Dis, 2020, 6(11):2926-2937]	PubMed: 33078609
In Vitro and In Vivo Activity, Tolerability and Mechanism of Action of BX795 as an Antiviral against Herpes Simplex Virus-2 Genital Infection [ Antimicrob Agents Chemother, 2020, AAC.00245-20]	PubMed: 32601167
Anti-HSV-1 effect of dihydromyricetin from Ampelopsis grossedentata via the TLR9-dependent anti-inflammatory pathway [ J Glob Antimicrob Resist, 2020, S2213-7165(20)30264-2]	PubMed: 33161114
Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing [ Sci Adv, 2020, 6(49)eabd9443]	PubMed: 33277262

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

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