IL1RA Rabbit Recombinant mAb

生物描述

特异性

IL1RA Rabbit Recombinant mAb detects endogenous level of total IL1RA.

背景

The interleukin-1 receptor antagonist (IL-1Ra) is a member of the IL-1 family that binds to IL-1 receptors but does not induce any intracellular response. The production of IL-1Ra is stimulated by many substances including adherent IgG, other cytokines, and bacterial or viral components. IL-1Ra is important in host defense against endotoxin-induced injury. IL-1Ra is produced by hepatic cells with the characteristics of an acute phase protein. Endogenous IL-1Ra is produced in numerous experimental animal models of disease as well as in human autoimmune and chronic inflammatory diseases. IL-1Ra is also an important natural antiinflammatory protein in arthritis, colitis, and granulomatous pulmonary disease.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse Rat
MW (kDa)	20kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Arend WP, et al. Annu Rev Immunol. 1998, 16:27-55.

Application Data

WB

IHC

IF