AF488 Mouse/human/rat EOMES Antibody [Dan11mag]

目录号:G2829

打印

生物描述

特异性
背景 Eomesodermin,即EOMES,是T-box家族的转录因子。在胚胎发育过程中,EOMES在调节滋养层分化、原肠胚形成、中胚层分层和大脑皮层发育中至关重要。在免疫系统中,EOMES参与CD8+ T细胞的活化、迁移和分化。与另一个T-box转录因子T-bet协同,EOMES诱导IFN-γ的产生并增强效应CD8+ T细胞的细胞毒性活性。EOMES已被证明是维持CD8+ T细胞长期记忆所必需的,并且对记忆和效应T细胞的稳态很重要。

使用信息

抗体应用 FCM, IHC 推荐用量 0.2 μg (0.4 μL) / million cells in 100 µL volume
反应性 Mouse, Bat, Human, Rat
抗体类型 Rat MW
储存液配方 Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
储存条件
(自收到货起)
Store at 4°C in the dark to avoid freeze-thaw cycles

Application Data

FCM

Validated by Selleck

  • Permeabilization of mouse splenocytes using Foxp3/Transcription Factor Staining Buffer Set (Permeabilization Reagent), followed by intranuclear staining using AF488 Mouse/human/rat EOMES Antibody [Dan11mag] (Selleck Cat.: G2829). Analyzed data are derived from cells within the lymphocyte gate.