生物描述

特异性

AMBP Rabbit Recombinant mAb detects endogenous levels of total AMBP.

背景

AMBP (Alpha-1-microglobulin/bikunin precursor) is a complex glycoprotein secreted in plasma. AMBP mRNA is strongly transcribed in liver parenchyma, pancreas, and intestine epithelium. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin is a glycoprotein that associates with other plasma proteins, and binds a chromophore formed during heme-binding and degradation. Alpha-1-microglobulin belongs to the superfamily of lipocalin transport proteins, has immunoregulatory properties and is involved in heme-catabolism. Bikunin, another protein, is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:500 1:50
反应性	Human
MW (kDa)	39kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Sánchez D, et al. Mech Dev. 2002, 117(1-2):293-8.

Application Data

WB

IHC